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Archive for November, 2005

Meridia

Tuesday, November 1st, 2005

Meridia, a diet drug, was first approved by the FDA in 1997, one year after the advisory committee voted 5-4 that the benefits of Meridia did not outweigh the risks. Meridia had received a review from an FDA medical officer concluding that a non-approval was recommended due to the significant increase in blood pressure and heart rate in many people. Meridia has now been associated with 29 deaths, including 19 due to adverse cardiovascular effects.

Meridia is found in 70 countries and has been used by 8.5 million people worldwide. But the sales success of Meridia has turned into a safety question. After two cardiovascular deaths occurred in Italy, the use of Meridia was suspended so that a safety review could be performed. This Meridia suspension in Italy was the first country movement to investigate the safety of the weight loss pill that led to a Europe-wide review of the drug. France and Great Britain have also banned the drug due to its adverse cardiovascular effects.

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